Crystal structure and expression patterns of prolyl 4-hydroxylases from Phytophthora capsici.
Identifieur interne : 000548 ( Main/Exploration ); précédent : 000547; suivant : 000549Crystal structure and expression patterns of prolyl 4-hydroxylases from Phytophthora capsici.
Auteurs : Weiwei Song [République populaire de Chine] ; Cancan Yang [République populaire de Chine] ; Chunyuan Zhu [République populaire de Chine] ; Paul F. Morris [États-Unis] ; Xiuguo Zhang [République populaire de Chine]Source :
- Biochemical and biophysical research communications [ 1090-2104 ] ; 2019.
Descripteurs français
- KwdFr :
- Acides cétoglutariques (composition chimique), Acides cétoglutariques (métabolisme), Cristallographie aux rayons X (MeSH), Domaine catalytique (MeSH), Génome (MeSH), Modèles moléculaires (MeSH), Peptides (composition chimique), Peptides (métabolisme), Phylogenèse (MeSH), Phytophthora (enzymologie), Phytophthora (génétique), Prolyl hydroxylases (composition chimique), Prolyl hydroxylases (métabolisme), Régulation de l'expression des gènes (MeSH), Séquence d'acides aminés (MeSH).
- MESH :
- composition chimique : Acides cétoglutariques, Peptides, Prolyl hydroxylases.
- enzymologie : Phytophthora.
- génétique : Phytophthora.
- métabolisme : Acides cétoglutariques, Peptides, Prolyl hydroxylases.
- Cristallographie aux rayons X, Domaine catalytique, Génome, Modèles moléculaires, Phylogenèse, Régulation de l'expression des gènes, Séquence d'acides aminés.
English descriptors
- KwdEn :
- Amino Acid Sequence (MeSH), Catalytic Domain (MeSH), Crystallography, X-Ray (MeSH), Gene Expression Regulation (MeSH), Genome (MeSH), Ketoglutaric Acids (chemistry), Ketoglutaric Acids (metabolism), Models, Molecular (MeSH), Peptides (chemistry), Peptides (metabolism), Phylogeny (MeSH), Phytophthora (enzymology), Phytophthora (genetics), Prolyl Hydroxylases (chemistry), Prolyl Hydroxylases (metabolism).
- MESH :
- chemical , chemistry : Ketoglutaric Acids, Peptides, Prolyl Hydroxylases.
- chemical , metabolism : Ketoglutaric Acids, Peptides, Prolyl Hydroxylases.
- enzymology : Phytophthora.
- genetics : Phytophthora.
- Amino Acid Sequence, Catalytic Domain, Crystallography, X-Ray, Gene Expression Regulation, Genome, Models, Molecular, Phylogeny.
Abstract
Prolyl 4-hydroxylases (P4Hs) are members of the Fe2+ and 2-oxoglutarate- dependent oxygenases family, which play central roles in the collagen stabilization, hypoxia sensing, and translational regulation in eukaryotes. Thus far, nothing is known about the role of P4Hs in development and pathogenesis in oomycetes. Here we show that the Phytophthora capsici genome contains five putative prolyl 4-hydroxylases. In mycelia, all P4Hs were downregulated in response to hypoxia, but the expression of PcP4H1 was most affected. Strikingly, Pc4H1 was upregulated more than 110 fold at the onset of infection, and Pc4H5 was upregulated seven fold, while the expression of other P4H's were unchanged. Similar to well-characterized P4H proteins, the crystallographic structure of PcP4H1 contains a highly conserved double-stranded β-helix core fold and catalytic residues. However, the binding affinity of 2-oxoglutarate to PcP4H1 is very low. The extended C-terminal α-helix bundle and longer β2-β3 disordered substrate binding loop may help in confirming the peptide target of this enzyme.
DOI: 10.1016/j.bbrc.2018.12.022
PubMed: 30551874
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Crystal structure and expression patterns of prolyl 4-hydroxylases from Phytophthora capsici.</title><author><name sortKey="Song, Weiwei" sort="Song, Weiwei" uniqKey="Song W" first="Weiwei" last="Song">Weiwei Song</name><affiliation wicri:level="1"><nlm:affiliation>College of Plant Protection, Shandong Agricultural University, Taian, 271018, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Plant Protection, Shandong Agricultural University, Taian, 271018</wicri:regionArea><wicri:noRegion>271018</wicri:noRegion></affiliation></author><author><name sortKey="Yang, Cancan" sort="Yang, Cancan" uniqKey="Yang C" first="Cancan" last="Yang">Cancan Yang</name><affiliation wicri:level="1"><nlm:affiliation>College of Plant Protection, Shandong Agricultural University, Taian, 271018, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Plant Protection, Shandong Agricultural University, Taian, 271018</wicri:regionArea><wicri:noRegion>271018</wicri:noRegion></affiliation></author><author><name sortKey="Zhu, Chunyuan" sort="Zhu, Chunyuan" uniqKey="Zhu C" first="Chunyuan" last="Zhu">Chunyuan Zhu</name><affiliation wicri:level="1"><nlm:affiliation>College of Life Sciences, Shandong Agricultural University, Taian, 271018, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Life Sciences, Shandong Agricultural University, Taian, 271018</wicri:regionArea><wicri:noRegion>271018</wicri:noRegion></affiliation></author><author><name sortKey="Morris, Paul F" sort="Morris, Paul F" uniqKey="Morris P" first="Paul F" last="Morris">Paul F. Morris</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Sciences, Bowling Green State University, Bowling Green, OH, 43403, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biological Sciences, Bowling Green State University, Bowling Green, OH, 43403</wicri:regionArea><wicri:noRegion>43403</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Xiuguo" sort="Zhang, Xiuguo" uniqKey="Zhang X" first="Xiuguo" last="Zhang">Xiuguo Zhang</name><affiliation wicri:level="1"><nlm:affiliation>College of Plant Protection, Shandong Agricultural University, Taian, 271018, China. Electronic address: zhxg@sdau.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Plant Protection, Shandong Agricultural University, Taian, 271018</wicri:regionArea><wicri:noRegion>271018</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2019">2019</date><idno type="RBID">pubmed:30551874</idno><idno type="pmid">30551874</idno><idno type="doi">10.1016/j.bbrc.2018.12.022</idno><idno type="wicri:Area/Main/Corpus">000593</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000593</idno><idno type="wicri:Area/Main/Curation">000593</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000593</idno><idno type="wicri:Area/Main/Exploration">000593</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Crystal structure and expression patterns of prolyl 4-hydroxylases from Phytophthora capsici.</title><author><name sortKey="Song, Weiwei" sort="Song, Weiwei" uniqKey="Song W" first="Weiwei" last="Song">Weiwei Song</name><affiliation wicri:level="1"><nlm:affiliation>College of Plant Protection, Shandong Agricultural University, Taian, 271018, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Plant Protection, Shandong Agricultural University, Taian, 271018</wicri:regionArea><wicri:noRegion>271018</wicri:noRegion></affiliation></author><author><name sortKey="Yang, Cancan" sort="Yang, Cancan" uniqKey="Yang C" first="Cancan" last="Yang">Cancan Yang</name><affiliation wicri:level="1"><nlm:affiliation>College of Plant Protection, Shandong Agricultural University, Taian, 271018, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Plant Protection, Shandong Agricultural University, Taian, 271018</wicri:regionArea><wicri:noRegion>271018</wicri:noRegion></affiliation></author><author><name sortKey="Zhu, Chunyuan" sort="Zhu, Chunyuan" uniqKey="Zhu C" first="Chunyuan" last="Zhu">Chunyuan Zhu</name><affiliation wicri:level="1"><nlm:affiliation>College of Life Sciences, Shandong Agricultural University, Taian, 271018, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Life Sciences, Shandong Agricultural University, Taian, 271018</wicri:regionArea><wicri:noRegion>271018</wicri:noRegion></affiliation></author><author><name sortKey="Morris, Paul F" sort="Morris, Paul F" uniqKey="Morris P" first="Paul F" last="Morris">Paul F. Morris</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Sciences, Bowling Green State University, Bowling Green, OH, 43403, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biological Sciences, Bowling Green State University, Bowling Green, OH, 43403</wicri:regionArea><wicri:noRegion>43403</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Xiuguo" sort="Zhang, Xiuguo" uniqKey="Zhang X" first="Xiuguo" last="Zhang">Xiuguo Zhang</name><affiliation wicri:level="1"><nlm:affiliation>College of Plant Protection, Shandong Agricultural University, Taian, 271018, China. Electronic address: zhxg@sdau.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Plant Protection, Shandong Agricultural University, Taian, 271018</wicri:regionArea><wicri:noRegion>271018</wicri:noRegion></affiliation></author></analytic><series><title level="j">Biochemical and biophysical research communications</title><idno type="eISSN">1090-2104</idno><imprint><date when="2019" type="published">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amino Acid Sequence (MeSH)</term><term>Catalytic Domain (MeSH)</term><term>Crystallography, X-Ray (MeSH)</term><term>Gene Expression Regulation (MeSH)</term><term>Genome (MeSH)</term><term>Ketoglutaric Acids (chemistry)</term><term>Ketoglutaric Acids (metabolism)</term><term>Models, Molecular (MeSH)</term><term>Peptides (chemistry)</term><term>Peptides (metabolism)</term><term>Phylogeny (MeSH)</term><term>Phytophthora (enzymology)</term><term>Phytophthora (genetics)</term><term>Prolyl Hydroxylases (chemistry)</term><term>Prolyl Hydroxylases (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Acides cétoglutariques (composition chimique)</term><term>Acides cétoglutariques (métabolisme)</term><term>Cristallographie aux rayons X (MeSH)</term><term>Domaine catalytique (MeSH)</term><term>Génome (MeSH)</term><term>Modèles moléculaires (MeSH)</term><term>Peptides (composition chimique)</term><term>Peptides (métabolisme)</term><term>Phylogenèse (MeSH)</term><term>Phytophthora (enzymologie)</term><term>Phytophthora (génétique)</term><term>Prolyl hydroxylases (composition chimique)</term><term>Prolyl hydroxylases (métabolisme)</term><term>Régulation de l'expression des gènes (MeSH)</term><term>Séquence d'acides aminés (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Ketoglutaric Acids</term><term>Peptides</term><term>Prolyl Hydroxylases</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Ketoglutaric Acids</term><term>Peptides</term><term>Prolyl Hydroxylases</term></keywords><keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Acides cétoglutariques</term><term>Peptides</term><term>Prolyl hydroxylases</term></keywords><keywords scheme="MESH" qualifier="enzymologie" xml:lang="fr"><term>Phytophthora</term></keywords><keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Phytophthora</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Phytophthora</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Phytophthora</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Acides cétoglutariques</term><term>Peptides</term><term>Prolyl hydroxylases</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Amino Acid Sequence</term><term>Catalytic Domain</term><term>Crystallography, X-Ray</term><term>Gene Expression Regulation</term><term>Genome</term><term>Models, Molecular</term><term>Phylogeny</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Cristallographie aux rayons X</term><term>Domaine catalytique</term><term>Génome</term><term>Modèles moléculaires</term><term>Phylogenèse</term><term>Régulation de l'expression des gènes</term><term>Séquence d'acides aminés</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Prolyl 4-hydroxylases (P4Hs) are members of the Fe<sup>2+</sup> and 2-oxoglutarate- dependent oxygenases family, which play central roles in the collagen stabilization, hypoxia sensing, and translational regulation in eukaryotes. Thus far, nothing is known about the role of P4Hs in development and pathogenesis in oomycetes. Here we show that the Phytophthora capsici genome contains five putative prolyl 4-hydroxylases. In mycelia, all P4Hs were downregulated in response to hypoxia, but the expression of PcP4H1 was most affected. Strikingly, Pc4H1 was upregulated more than 110 fold at the onset of infection, and Pc4H5 was upregulated seven fold, while the expression of other P4H's were unchanged. Similar to well-characterized P4H proteins, the crystallographic structure of PcP4H1 contains a highly conserved double-stranded β-helix core fold and catalytic residues. However, the binding affinity of 2-oxoglutarate to PcP4H1 is very low. The extended C-terminal α-helix bundle and longer β2-β3 disordered substrate binding loop may help in confirming the peptide target of this enzyme.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30551874</PMID><DateCompleted><Year>2019</Year><Month>09</Month><Day>11</Day></DateCompleted><DateRevised><Year>2019</Year><Month>09</Month><Day>11</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1090-2104</ISSN><JournalIssue CitedMedium="Internet"><Volume>508</Volume><Issue>4</Issue><PubDate><Year>2019</Year><Month>01</Month><Day>22</Day></PubDate></JournalIssue><Title>Biochemical and biophysical research communications</Title><ISOAbbreviation>Biochem Biophys Res Commun</ISOAbbreviation></Journal><ArticleTitle>Crystal structure and expression patterns of prolyl 4-hydroxylases from Phytophthora capsici.</ArticleTitle><Pagination><MedlinePgn>1011-1017</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0006-291X(18)32665-2</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.bbrc.2018.12.022</ELocationID><Abstract><AbstractText>Prolyl 4-hydroxylases (P4Hs) are members of the Fe<sup>2+</sup> and 2-oxoglutarate- dependent oxygenases family, which play central roles in the collagen stabilization, hypoxia sensing, and translational regulation in eukaryotes. Thus far, nothing is known about the role of P4Hs in development and pathogenesis in oomycetes. Here we show that the Phytophthora capsici genome contains five putative prolyl 4-hydroxylases. In mycelia, all P4Hs were downregulated in response to hypoxia, but the expression of PcP4H1 was most affected. Strikingly, Pc4H1 was upregulated more than 110 fold at the onset of infection, and Pc4H5 was upregulated seven fold, while the expression of other P4H's were unchanged. Similar to well-characterized P4H proteins, the crystallographic structure of PcP4H1 contains a highly conserved double-stranded β-helix core fold and catalytic residues. However, the binding affinity of 2-oxoglutarate to PcP4H1 is very low. The extended C-terminal α-helix bundle and longer β2-β3 disordered substrate binding loop may help in confirming the peptide target of this enzyme.</AbstractText><CopyrightInformation>Copyright © 2018 Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Song</LastName><ForeName>Weiwei</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>College of Plant Protection, Shandong Agricultural University, Taian, 271018, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yang</LastName><ForeName>Cancan</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>College of Plant Protection, Shandong Agricultural University, Taian, 271018, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhu</LastName><ForeName>Chunyuan</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>College of Life Sciences, Shandong Agricultural University, Taian, 271018, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Morris</LastName><ForeName>Paul F</ForeName><Initials>PF</Initials><AffiliationInfo><Affiliation>Department of Biological Sciences, Bowling Green State University, Bowling Green, OH, 43403, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Xiuguo</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>College of Plant Protection, Shandong Agricultural University, Taian, 271018, China. Electronic address: zhxg@sdau.edu.cn.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2018</Year><Month>12</Month><Day>11</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Biochem Biophys Res Commun</MedlineTA><NlmUniqueID>0372516</NlmUniqueID><ISSNLinking>0006-291X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007656">Ketoglutaric Acids</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010455">Peptides</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 1.14.11.-</RegistryNumber><NameOfSubstance UI="D064828">Prolyl Hydroxylases</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000595" MajorTopicYN="N">Amino Acid Sequence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020134" MajorTopicYN="N">Catalytic Domain</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018360" MajorTopicYN="N">Crystallography, X-Ray</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005786" MajorTopicYN="N">Gene Expression Regulation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016678" MajorTopicYN="N">Genome</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007656" MajorTopicYN="N">Ketoglutaric Acids</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008958" MajorTopicYN="N">Models, Molecular</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010455" MajorTopicYN="N">Peptides</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010802" MajorTopicYN="N">Phylogeny</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010838" MajorTopicYN="N">Phytophthora</DescriptorName><QualifierName UI="Q000201" MajorTopicYN="Y">enzymology</QualifierName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D064828" MajorTopicYN="N">Prolyl Hydroxylases</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Crystal structure</Keyword><Keyword MajorTopicYN="Y">Expression pattern</Keyword><Keyword MajorTopicYN="Y">Prolyl-4 hydroxylase</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year><Month>11</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2018</Year><Month>12</Month><Day>04</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2018</Year><Month>12</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>9</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2018</Year><Month>12</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">30551874</ArticleId><ArticleId IdType="pii">S0006-291X(18)32665-2</ArticleId><ArticleId IdType="doi">10.1016/j.bbrc.2018.12.022</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li><li>États-Unis</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Song, Weiwei" sort="Song, Weiwei" uniqKey="Song W" first="Weiwei" last="Song">Weiwei Song</name></noRegion><name sortKey="Yang, Cancan" sort="Yang, Cancan" uniqKey="Yang C" first="Cancan" last="Yang">Cancan Yang</name><name sortKey="Zhang, Xiuguo" sort="Zhang, Xiuguo" uniqKey="Zhang X" first="Xiuguo" last="Zhang">Xiuguo Zhang</name><name sortKey="Zhu, Chunyuan" sort="Zhu, Chunyuan" uniqKey="Zhu C" first="Chunyuan" last="Zhu">Chunyuan Zhu</name></country><country name="États-Unis"><noRegion><name sortKey="Morris, Paul F" sort="Morris, Paul F" uniqKey="Morris P" first="Paul F" last="Morris">Paul F. Morris</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/PhytophthoraV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000548 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000548 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= PhytophthoraV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:30551874
|texte= Crystal structure and expression patterns of prolyl 4-hydroxylases from Phytophthora capsici.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:30551874" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a PhytophthoraV1
| This area was generated with Dilib version V0.6.38. |  |